The most effective clinical brightener joins forces with effective botanicals to begin the lightening process. Medically proven hydroquinone, bearberrry extract, Kojic acid and salicylic acid go deep within the skin to lighten brown spots and refresh skin for an overall lighter, brighter complexion. Directions for use: Use once daily for a week then progress to twice daily as tolerated. After using REVERSE 1, apply Prepare with a gauze pad to entire face. Avoid eyes. Allow to dry; do not rinse off. From Rodan + Fields, creators of Proactiv.