Help the skin retain more moisture to make it smoother, healthier and younger-looking. If you want the most effective Glycolic acid formulations available, rely on the power of physician-strength Gly Derm. This product is used to improve the overall appearance and texture of the skin. The plus line which contains twice the percentage of glycolic acid should only be used by those customers who have used glycolics previously and demonstrated tolerance to these concentrations without irritation.